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Updated: Mar 9, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with
Marcella Amaral Horta Barbosa Vieira1, Maria Isabel Ramos Saraiva2, Larissa Karine Leite da Silva2
1MD (Graduate degree in Dermatology), Resident in Dermatology, São Paulo, SP, Brazil.
Abstract:
We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.
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