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Updated: Mar 9, 2026

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
Published on: April 11, 2025
Silicon-on-insulator-based complementary metal oxide semiconductor integrated optoelectronic platform for biomedical
Muhammad Mujeeb-U-Rahman1, Axel Scherer2
1Information Technology University, Electrical Engineering, 6th Floor Arfa Software Technology Park, Lahore 54000, Pakistan.
Wireless power harvesting and telemetry in microscale optical devices enable precise biological manipulation. Silicon-on-insulator platforms integrate optoelectronics and microelectronics for advanced biomedical applications.
Area of Science:
- Biomedical Engineering
- Optoelectronics
- Microelectronics
Background:
- Microscale optical devices are crucial for localized biological manipulation, including neural recording and targeted cancer cell delivery.
- Current methods often require extreme optical focusing or nanoparticles, limiting in vivo applications.
- Wireless power harvesting and telemetry offer a promising alternative for untethered microsystem operation.
Purpose of the Study:
- To present design and integration techniques for optical power harvesting structures with complementary metal-oxide-semiconductor (CMOS) platforms.
- To enable complex in vivo applications like actuating single nerves without stringent focusing requirements.
- To leverage Silicon-on-Insulator (SOI) technology for miniaturized optoelectronic and microelectronic device fabrication on a single substrate.
Main Methods:
- Utilizing near-infrared biomedical optics for efficient optical power harvesting.
- Employing Silicon-on-Insulator (SOI) based platforms for integrated optoelectronic and microelectronic device fabrication.
- Integrating optical power harvesting structures with monolithically integrated electronics on CMOS platforms.
Main Results:
- Demonstrated effective optical power harvesting using near-infrared optics at submillimeter scales.
- Successfully integrated optical power harvesting with SOI-based CMOS platforms and microelectronics.
- Showcased the potential for creating miniaturized, untethered optoelectronic biomedical systems.
Conclusions:
- SOI platforms offer a robust architecture for developing advanced optoelectronic biomedical systems.
- Optical power harvesting integrated with CMOS technology enables sophisticated in vivo applications.
- These advancements pave the way for novel biomedical implants and lab-on-chip systems.
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