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Cardiometabolic risk is associated with the severity of sleep-disordered breathing in children with obesity

Laurie Isacco1, Johanna Roche2, Sylvain Quinart3

  • 1EA3920, Exercise Performance Health Innovation Platform, University of Bourgogne Franche-Comte, France, CHRU Jean Minjoz. Boulevard Fleming, F-25000 Besançon, France; Sports Science Faculty, University of Bourgogne Franche-Comte, France, 31 chemin de l'Epitaphe. F-25000 Besançon, France.

Physiology & Behavior
|December 21, 2016
PubMed

Insights

Pediatric obesity and sleep-disordered breathing (SDB) share cardiometabolic risks. SDB severity, not presence, impacts risk scores in obese children, independent of physical activity level (PAL).

Area of Science:

  • Pediatric Endocrinology
  • Sleep Medicine
  • Cardiology

Background:

  • Pediatric obesity is a growing concern linked to sleep-disordered breathing (SDB).
  • Both conditions share adverse cardiometabolic health outcomes.
  • Physical activity level (PAL) may influence sleep and metabolic health.

Purpose of the Study:

  • Investigate the association between metabolic syndrome (MS) and SDB in childhood obesity.
  • Examine the impact of SDB severity on cardiometabolic risk and PAL in obese children.

Main Methods:

  • Assessed 83 obese children (age 10.7±2.7 years) for maturation, anthropometrics, and cardiometabolic markers.
  • Evaluated PAL using a step test and SDB via overnight sleep monitoring.
  • Determined MS presence and calculated continuous cardiometabolic risk scores (MetScoreBMI, MetScoreWC).

Main Results:

  • Obese children with and without MS showed similar SDB prevalence.
  • SDB severity correlated with higher insulin, MetScoreBMI, and MetScoreWC (p<0.05).
  • No association was found between SDB and PAL.

Conclusions:

  • SDB severity influences cardiometabolic risk factors in obese children, despite diagnostic consensus challenges.
  • Further research is needed on PAL's role in metabolic and sleep issues in pediatric obesity.
Abstract

Keywords:
ChildrenMetScoreObesityPhysical activitySleep

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