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Chitosan based nanofibers in bone tissue engineering.

K Balagangadharan1, S Dhivya1, N Selvamurugan1

  • 1Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur, Tamil Nadu, India.

International Journal of Biological Macromolecules
|December 21, 2016
PubMed
Summary
This summary is machine-generated.

This review explores chitosan nanofibers for bone tissue engineering. These advanced biomaterials show promise for creating effective bone grafts to regenerate damaged bone tissue.

Keywords:
Bone tissue engineeringChitosanNanofibers

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Nanotechnology

Background:

  • Bone tissue engineering aims to create biosynthetic bone grafts for bone regeneration.
  • Electrospinning is a key technique for fabricating nanofibrous scaffolds with properties similar to the extracellular matrix.

Purpose of the Study:

  • To review chitosan (CS) and its composites prepared as nanofibers.
  • To assess their suitability for bone tissue engineering applications.

Main Methods:

  • Review of existing literature on chitosan nanofibers.
  • Analysis of properties relevant to bone regeneration.

Main Results:

  • Electrospun nanofibers offer high surface area, porosity, and stability.
  • Chitosan nanofibers provide structural and biochemical cues beneficial for bone regeneration.

Conclusions:

  • Chitosan nanofibers are a promising material for bone tissue engineering scaffolds.
  • Their unique properties accelerate bone regeneration and mineralization.