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Invasive group G streptococcal infection in a paediatric patient.
Sejal Makvana Bhavsar1, Gail F Shust1
1Icahn School of Medicine at Mount Sinai Department of Pediatrics, Division of Pediatric Infectious Diseases, New York, New York, USA.
BMJ Case Reports
|December 21, 2016
Summary
A pediatric case of group G streptococcal bacteraemia and vertebral osteomyelitis in a patient with Gaucher disease was successfully treated with antibiotics. This highlights effective management of serious infections in immunocompromised children.
Area of Science:
- Pediatric Infectious Diseases
- Bacteriology
- Bone Infections
Background:
- Group G Streptococcus (GGS) is an uncommon cause of invasive infections in children.
- Vertebral osteomyelitis is a serious bone infection that can lead to significant morbidity.
- Gaucher disease type 1 is a lysosomal storage disorder that may increase susceptibility to infections.
Observation:
- A 14-year-old girl with Gaucher disease type 1 presented with severe thoracolumbar pain.
- Blood cultures revealed group G streptococcal bacteraemia.
- Imaging confirmed vertebral osteomyelitis.
Findings:
- The patient received a 4-week course of targeted antibiotic therapy.
- Clinical improvement was observed following antibiotic treatment.
- Group G streptococcal bacteraemia and vertebral osteomyelitis were successfully managed.
Implications:
- This case underscores the importance of prompt diagnosis and treatment of invasive GGS infections in pediatric patients.
- Effective antibiotic management can lead to favorable outcomes even in immunocompromised individuals with complex conditions like Gaucher disease.
- Further research into GGS epidemiology and risk factors in pediatric populations with underlying metabolic disorders is warranted.
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