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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Approach to a tremor patient.
Soumya Sharma1, Sanjay Pandey1
1Department of Neurology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India.
Annals of Indian Academy of Neurology
|December 21, 2016
Summary
Tremors are common involuntary movements. Classification helps identify causes, with treatments ranging from medication to deep brain stimulation and botulinum toxin injections for specific types.
Area of Science:
- Neurology
- Movement Disorders
Background:
- Tremors are prevalent, representing the most common movement disorders.
- Defined as rhythmic, involuntary oscillatory movements around joints, tremors vary in etiology and clinical presentation.
Purpose of the Study:
- To review the classification, diagnosis, and treatment of various tremor types.
- To highlight the importance of accurate classification for identifying underlying causes.
Main Methods:
- Clinical classification based on rest or action, frequency, amplitude, and body part involved.
- Review of common tremor etiologies including Parkinsonian, Essential Tremor (ET), and psychogenic tremors.
- Assessment methods including clinical rating scales and electrophysiological measurements.
Main Results:
- Parkinsonian tremor is a common cause of rest tremor; Essential Tremor (ET) and enhanced physiological tremor are common action tremors.
- Isolated head tremor may indicate dystonia, while isolated voice tremor might be part of the ET spectrum.
- Psychogenic tremor diagnosis requires specific clinical signs, not exclusion.
Conclusions:
- Accurate tremor classification is crucial for etiological diagnosis.
- Treatment is symptomatic, with medications effective for some Essential Tremor cases; deep brain stimulation and botulinum toxin injections are alternative therapies for refractory or specific tremor types.
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