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Recurrent nephrolithiasis associated with keratinizing desquamative squamous metaplasia
Ryan Fitzpatrick1, Luke F Reynolds, James D Watterson
1Division of Urology, Department of Surgery, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
The Canadian Journal of Urology
|December 21, 2016
Summary
Keratinizing desquamative squamous metaplasia (KDSM) of the renal pelvis is a rare condition. Percutaneous surgery effectively removes stones and KDSM, allowing for urothelial surveillance.
Area of Science:
- Urology
- Pathology
Background:
- Keratinizing desquamative squamous metaplasia (KDSM) of the renal pelvis is a rare condition with uncertain malignant potential.
- Previous literature suggests KDSM is benign and amenable to endoscopic treatment.
Observation:
- Two cases of renal pelvis KDSM were reviewed, both associated with recurrent urolithiasis.
- Patients presented with symptoms suggestive of KDSM-induced obstruction and infection.
Findings:
- Both patients underwent successful percutaneous nephrolithotomy with complete removal of renal calculi and KDSM plaques.
- Histopathological examination confirmed KDSM and ruled out malignancy in both cases.
Implications:
- Percutaneous surgery offers a viable option for eradicating renal calculi and KDSM from the collecting system.
- This approach facilitates thorough oncologic surveillance of the urothelium, addressing concerns about KDSM's malignant potential.
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