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3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

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Physically Realizable Three-Dimensional Bone Prosthesis Design With Interpolated Microstructures.

Andrew D Cramer¹, Vivien J Challis¹, Anthony P Roberts¹

¹School of Mathematics and Physics, The University of Queensland, Brisbane QLD 4072, Australia

Journal of Biomechanical Engineering

|December 21, 2016

Summary

This summary is machine-generated.

This study introduces a novel method for designing porous femoral implants with adaptable microstructures. These advanced designs reduce stress and bone resorption, outperforming traditional homogeneous implants and proving manufacturable.

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Intravital Longitudinal Imaging of Vascular Dynamics in the Calvarial Bone Marrow

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Area of Science:

Biomaterials Engineering
Orthopedic Implant Design
Computational Mechanics

Background:

Femoral implants are crucial in orthopedic surgery, but traditional designs face challenges like stress shielding and bone resorption.
Optimizing implant microstructure is key to improving long-term bone-prosthetic integration and implant survival.
Current design methodologies often overlook the potential of spatially varying microstructures.

Purpose of the Study:

To develop a novel computational approach for designing three-dimensional, physically realizable porous femoral implants.
To optimize implant designs by minimizing shear stress at the bone-prosthetic interface and constraining bone resorption.
To investigate the impact of varying microstructures on implant performance and manufacturability.

Main Methods:

Utilized a simplified design domain for optimization, incorporating strain energy-based bone resorption constraints.
Employed shape interpolation to construct microstructure sets from multifunctional base microstructures.
Evaluated designs with homogeneous versus spatially varying microstructures for a femoral implant application.

Main Results:

Designs incorporating spatially varying microstructures significantly outperformed those with homogeneous microstructures.
The selection of specific microstructure sets influenced optimization outcomes and final implant designs.
A proof-of-concept metal prototype fabricated using selective laser melting (SLM) validated the proposed design approach's manufacturability.

Conclusions:

The developed design methodology enables the creation of advanced porous femoral implants with tailored microstructures.
Spatially varying microstructures offer superior performance compared to homogeneous designs for femoral implants.
The approach demonstrates a viable pathway for fabricating patient-specific, high-performance orthopedic implants.