Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extracellular vesicles participate in proteostasis and heat shock adaptation in <i>Plasmodium falciparum</i>.

Emerging microbes & infections·2026
Same author

Unveiling challenges and successes for graduate students in a post-pandemic era.

Journal of American college health : J of ACH·2026
Same author

Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[<i>h</i>]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity.

Biomolecules·2026
Same author

Structure-based virtual screening, in vitro and in silico analysis identified novel potent m6A demethylase FTO inhibitors as promising neurotherapeutic agents.

European journal of medicinal chemistry·2026
Same author

Design and Synthesis of Dualsteric Muscarinic M5 Receptor Ligands Reveal G Protein Bias.

ACS chemical neuroscience·2026
Same author

What you see is what you get: High degree of alignment accuracy with hand-held computer-aided technology when comparing intraoperative alignment to postoperative radiographs in direct anterior total hip arthroplasty.

Journal of orthopaedic surgery (Hong Kong)·2026

Related Experiment Video

Updated: Mar 9, 2026

A11-positive &#946;-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

12.7K

Special Issue: "Molecules against Alzheimer".

Michael Decker1, Diego Muñoz-Torrero2

  • 1Pharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany. michael.decker@uni-wuerzburg.de.

Molecules (Basel, Switzerland)
|December 22, 2016
PubMed
Summary

Researchers are developing new molecules and therapies to combat Alzheimer's disease (AD). This includes novel drug candidates, diagnostic agents, and therapeutic strategies targeting key biological pathways involved in AD progression.

Keywords:
Alzheimer’s diseasedrug discoveryhybrid moleculesimaging agentsmulti-target-directed moleculesneurogenic moleculesneuroprotectantspolypharmacologyrational design

More Related Videos

Selection of Aptamers for Amyloid &#946;-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

20.0K
Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model
06:02

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on: July 26, 2011

37.5K

Related Experiment Videos

Last Updated: Mar 9, 2026

A11-positive &#946;-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

12.7K
Selection of Aptamers for Amyloid &#946;-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

20.0K
Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model
06:02

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on: July 26, 2011

37.5K

Area of Science:

  • Neuroscience and Pharmacology
  • Drug Discovery and Development

Background:

  • Alzheimer's disease (AD) is a leading cause of death, necessitating novel therapeutic and diagnostic strategies.
  • Current research focuses on multifaceted approaches targeting various pathological hallmarks of AD.

Discussion:

  • This Special Issue highlights the design, synthesis, and profiling of compounds targeting cholinesterases, beta-amyloid, oxidative stress, and other AD-related pathways.
  • Exploration of tau protein imaging agents and therapeutic interventions like lithium and intranasal insulin for AD management.

Key Insights:

  • Novel small molecules and therapeutic agents demonstrate potential against key biological targets in Alzheimer's disease.
  • Advanced diagnostic tools, including tau imaging, are being developed for earlier and more accurate AD detection.

Outlook:

  • Continued research into molecular mechanisms and therapeutic targets offers promise for future AD treatments.
  • Integration of diagnostic and therapeutic advancements is crucial for effective Alzheimer's disease management.