Implementation of a Nutrition Program Reduced Post-Discharge Growth Restriction in Thai Very Low Birth Weight Preterm
Suchada Japakasetr1, Chutima Sirikulchayanonta2, Umaporn Suthutvoravut3
1Department of Nutrition, Faculty of Public Health, Mahidol University, Bangkok 10400, Thailand. scdj01@yahoo.com.
Insights
The preterm infant, post-discharge nutrition (PIN) program effectively reduced growth restriction in very low birth weight (VLBW) preterm infants. This nutritional intervention improved infant weight and head circumference by six months corrected age.
Area of Science:
- Neonatology
- Pediatric Nutrition
- Growth and Development
Background:
- Very low birth weight (VLBW) preterm infants face significant risks of post-discharge growth restriction.
- Cumulative protein and energy deficits during hospitalization and early post-discharge periods contribute to this vulnerability.
Purpose of the Study:
- To evaluate the effectiveness of a preterm infant, post-discharge nutrition (PIN) program.
- To assess the program's impact on reducing post-discharge growth restriction in Thai VLBW preterm infants.
Main Methods:
- A prospective, non-randomized interventional cohort study.
- Comparison of 22 VLBW infants in the PIN program with 22 receiving conventional nutrition.
- Monthly growth monitoring until six months corrected age (6-moCA).
Main Results:
- Intervention infants showed significantly greater body weights (p = 0.013) and head circumferences (p = 0.009).
- A higher proportion of the PIN group achieved standard weight by 4-moCA (p = 0.027) and 6-moCA (p = 0.007).
- The PIN group also demonstrated significantly improved head circumference by 6-moCA (p = 0.004).
Conclusions:
- The PIN program significantly reduced post-discharge growth restriction in VLBW preterm infants.
- The intervention positively impacted key growth parameters, including weight and head circumference.
- Further research is recommended to explore the long-term effects of the PIN program on infant growth and development.
Abstract:
Very low birth weight (VLBW) preterm infants are vulnerable to growth restriction after discharge due to cumulative protein and energy deficits during their hospital stay and early post-discharge period. The current study evaluated the effectiveness of the preterm infant, post-discharge nutrition (PIN) program to reduce post-discharge growth restriction in Thai VLBW preterm infants. A prospective, non-randomized interventional cohort study was undertaken to assess the growth of 22 VLBW preterm infants who received the PIN program and compared them with 22 VLBW preterm infants who received conventional nutrition services. Infant's growth was recorded monthly until the infants reached six months' corrected age (6-moCA). Intervention infants had significantly greater body weights (p = 0.013) and head circumferences (p = 0.009). Also, a greater proportion of the intervention group recovered their weight to the standard weight at 4-moCA (p = 0.027) and at 6-moCA (p = 0.007) and their head circumference to the standard head circumference at 6-moCA (p = 0.004) compared to their historical comparison counterparts. Enlistment in the PIN program thus resulted in significantly reduced post-discharge growth restriction in VLBW preterm infants. Further research on longer term effects of the program on infant's growth and development is warranted.
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