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Updated: Mar 9, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Antimicrobial usage and resistance in beef production
Andrew Cameron1, Tim A McAllister2
1Faculty of Veterinary Medicine, University of Calgary, Calgary, AB Canada ; Agriculture and Agri-Food Canada, Lethbridge, AB Canada.
Antimicrobial use in beef cattle drives resistance in bacteria and genes within the animal and food supply. This poses risks to animal health and public health through potential transmission to humans.
Area of Science:
- Veterinary Microbiology
- Food Safety
- Public Health
Background:
- Antimicrobials are integral to intensive beef production for animal health and growth promotion.
- Their use exerts selective pressure, fostering antimicrobial resistance (AMR) in bovine-associated bacteria and their genes.
- This resistance impacts animal health, production efficiency, and poses potential public health concerns.
Approach:
- This review synthesizes current antimicrobial use in beef production.
- It examines AMR prevalence in key bovine pathogens.
- The study analyzes the impact of antimicrobials on the bovine microbiota and the beef production resistome.
Key Points:
- Antimicrobial administration selects for resistance genes and resistant bacteria in cattle.
- Bovine pathogens can acquire and spread resistance via horizontal gene transfer.
- AMR in beef production is linked to food chain contamination and human health risks.
Conclusions:
- Understanding antimicrobial use and AMR dynamics in beef production is crucial.
- Mitigating AMR spread is essential for sustainable agriculture and public health protection.
- Further research is needed to address AMR in the food production continuum.
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