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Updated: Mar 9, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Takotsubo Cardiomyopathy in Traumatic Brain Injury
Chun Fai Cheah1,2, Mario Kofler1, Alois Josef Schiefecker1
1Department of Neurology, Neurological Intensive Care Unit, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Background:
Takotsubo cardiomyopathy (TC) is a well-known complication after aneurysmal subarachnoid hemorrhage and has been rarely described in patients with traumatic brain injury (TBI).
Methods:
Case report and review of literature.
Results:
Here, we report a 73-year-old woman with mild traumatic brain injury (TBI) presenting in cardiogenic shock. Takotsubo cardiomyopathy (TC) was diagnosed by repeated echocardiography. Cardiovascular support by inotropic agents led to hemodynamic stabilization after initiation of levosimendan. Cardiac function fully recovered within 21 days. We performed an in-depth literature review and identified 16 reported patients with TBI and TC. Clinical course and characteristics are discussed in the context of our patient.
Conclusion:
Takotsubo cardiomyopathy is under-recognized after TBI and may negatively impact outcome if left untreated.
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