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Karina Oyarce Merino1, Macarena Valladares Vega, Roberto Elizondo-Vega

  • 1Facultad de Medicina. Universidad San Sebastián. Concepción, Chile. aniobregon@gmail.com.

Nutricion Hospitalaria
|December 22, 2016
PubMed
Summary

Hedonic appetite regulation in children, alongside genetic profiles, can predict future obesity. Further research is needed to identify the best predictive parameters for adult obesity development.

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Area of Science:

  • Pediatrics
  • Genetics
  • Nutritional Science

Background:

  • Global obesity rates are rising due to increased sedentary lifestyles, high-fat/sugar diets, and genetic factors.
  • Early identification of obesity predisposition in children is crucial for adult health outcomes.

Purpose of the Study:

  • To review concepts of eating behavior, focusing on hedonic regulation as a potential predictor of childhood obesity.
  • To explore the link between genetic profiles, eating behavior, and obesity risk.

Main Methods:

  • Literature review of childhood obesity, homeostatic and hedonic regulation, and associated genetic parameters.
  • Inclusion of studies on animals and humans (adults and children, with emphasis on children).

Main Results:

  • Analysis of cellular mechanisms regulating food intake and eating behavior studies in children.
  • Identification of research gaps in predicting childhood obesity.

Conclusions:

  • Hedonic appetite regulation and genetic profiles (e.g., dopamine receptors) are potential predictors of childhood obesity.
  • More research is required to define optimal parameters for predicting adult obesity development.
Keywords:
Obesidad infantil. Conducta alimentaria. Sistema de recompensa cerebral. Dopamina.

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