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Updated: Aug 11, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
Standardization of intralesional meglumine antimoniate treatment for cutaneous leishmaniasis
Maria Cristina de Oliveira Duque1,2, Érica de Camargo Ferreira E Vasconcellos3, Maria Inês Fernandes Pimentel3
1Secretaria Municipal de Saúde de Timóteo, Timóteo, Minas Gerais, Brazil.
Introduction::
Intralesional treatment for cutaneous leishmaniasis has been applied for over 30 years at the Oswaldo Cruz Foundation, Rio de Janeiro, with good therapeutic results and without relevant systemic toxicity.
Methods:
Meglumine antimoniate was injected subcutaneously, using a long medium-caliber needle (for example, 30mm × 0.8mm); patients received 1-3 injections, with 15-day intervals.
Results:
The technique is described in detail sufficient to enable replication.
Conclusions::
The treatment of cutaneous leishmaniasis with intralesional meglumine antimoniate is a simple, effective, and safe technique, which may be used in basic healthcare settings.
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