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Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond

James D Vasta1, Amit Choudhary1, Katrina H Jensen1

  • 1Department of Biochemistry, ‡Graduate Program in Biophysics, and §Department of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.

Biochemistry
|December 22, 2016
PubMed

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