Related Experiment Video
Updated: Mar 9, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Pilot Testing a Web-Based System for the Assessment and Management of Chemotherapy-Induced Peripheral Neuropathy
Robert Knoerl1, William N Dudley, Gloria Smith
1Author Affiliations: University of Michigan School of Nursing (Mr Knoerl, Mss Bridges and Kanzawa-Lee, and Dr Lavoie Smith), Ann Arbor; School of Health and Human Sciences, University of North Carolina at Greensboro (Dr Dudley); and University of Michigan Health System (Ms Smith), Ann Arbor.
The Carevive platform helps patients report chemotherapy-induced peripheral neuropathy symptoms. While feasible, patients found it more usable and satisfactory than providers, who faced time and login issues.
Area of Science:
- Oncology
- Patient Care Technology
- Neurology
Background:
- Chemotherapy-induced peripheral neuropathy (CIPN) presents significant clinical challenges.
- Existing assessment and management strategies are often hindered by practical barriers.
- Novel digital health solutions are needed to improve CIPN care delivery.
Purpose of the Study:
- To evaluate patient and provider perspectives on the feasibility, usability, acceptability, and satisfaction with the Carevive Care Planning System.
- To assess the potential of a web-based platform in managing CIPN symptoms.
- To identify barriers and facilitators for adopting digital health tools in oncology care.
Main Methods:
- A single-arm, pretest/posttest, prospective study design was employed.
- Twenty-five women with breast cancer undergoing neurotoxic chemotherapy participated.
- Six advanced practice providers were recruited from an academic hospital setting.
- Patients reported neuropathy symptoms via the Carevive system on a tablet during three consecutive clinic visits.
- The Diffusion of Innovations Theory guided the evaluation framework.
Main Results:
- The Carevive platform demonstrated feasibility for use in clinical practice.
- Patients reported higher usability, acceptability, and satisfaction compared to providers.
- Providers expressed dissatisfaction related to the time commitment and login difficulties associated with the platform.
Conclusions:
- The Carevive platform shows promise for screening neuropathy symptoms and implementing evidence-based management strategies.
- Addressing provider-related issues, such as time and technical access, is crucial for successful adoption.
- Further refinement of the platform may enhance its utility in routine oncology care for CIPN management.
More Related Videos
05:18Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
Published on: October 6, 2023
07:02A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Published on: February 11, 2019
Related Concept Videos
Peripheral Artery Disease IV: Nursing Management
Peripheral Artery Disease III: Interprofessional Care