Related Experiment Video

Updated: Mar 9, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

21.0K

Comorbid Conditions are Associated With Emergency Department Visits, Hospitalizations, and Medical Charges of

Guang-Ming Han1, Xiao-Feng Han

  • 1From the *Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu, PR China; †Nebraska Department of Health and Human Services, Lincoln, NE; and ‡Department of Epidemiology, University of Nebraska Medical Center, Omaha, NE.

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
|December 22, 2016
PubMed

Insights

Comorbid conditions significantly increase healthcare utilization and medical costs for patients with systemic lupus erythematosus (SLE). Identifying these comorbidities is crucial for managing SLE patient care and reducing healthcare expenses.

Area of Science:

  • Rheumatology
  • Health Services Research
  • Public Health

Background:

  • Comorbidities increase mortality and healthcare costs in systemic lupus erythematosus (SLE).
  • Understanding comorbidities linked to healthcare utilization is vital for SLE patient management.
  • Emergency department visits and hospitalizations significantly impact medical costs for SLE patients.

Purpose of the Study:

  • To investigate the association between comorbidities and healthcare utilization in SLE patients.
  • To examine the relationship between comorbidities and medical charges for SLE patients.

Main Methods:

  • Utilized Nebraska statewide emergency department and hospital discharge data from 2007-2012.
  • Defined SLE using International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) code 710.0.
  • Analyzed comorbid conditions in SLE patients compared to a non-SLE cohort.

Main Results:

  • Patients with SLE exhibited more comorbid conditions than those without SLE.
  • Common comorbidities for emergency department visits included pain, infections, and digestive symptoms.
  • Frequent comorbidities for hospitalizations involved infections, cardiovascular diseases, COPD, and mood disorders.
  • The number of comorbidities correlated significantly with longer hospital stays and increased hospital charges for SLE patients.

Conclusions:

  • Comorbid conditions are demonstrably linked to increased healthcare utilization among SLE patients.
  • Findings highlight the substantial impact of comorbidities on medical charges for SLE patients.
  • This study underscores the importance of managing comorbidities to mitigate healthcare utilization and costs in SLE.
Abstract

More Related Videos

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

18.8K

Related Concept Videos

Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
292
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
4.0K
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
403
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
790
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
860
Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
76