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Updated: Mar 9, 2026
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
MACULAR MICROCYSTS IN SCHWARTZ-MATSUO SYNDROME
Xuejing Chen1, Grace M Richter, Joseph Caprioli
1Department of Ophthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Purpose:
To describe a case of macular microcysts associated with advanced secondary glaucoma from Schwartz-Matsuo syndrome.
Methods:
Clinical presentation, color fundus photography, optic disk photography, visual fields, and optical coherence tomography are presented.
Results:
A 32-year-old woman presented with advanced, unilateral secondary glaucoma associated with a macula-on rhegmatogenous retinal detachment. She was diagnosed with Schwartz-Matsuo syndrome. Spectral domain optical coherence tomography showed macular microcystic changes in the paracentral retina at the level of the inner nuclear layer.
Conclusion:
Macular microcystic changes in the paracentral inner nuclear layer on spectral domain optical coherence tomography have been described in eyes with optic atrophy associated with a variety of diseases. This is the first described case of macular microcysts associated with advanced secondary glaucoma from Schwartz-Matsuo syndrome and may offer insights into the pathogenesis of these microcysts.
