Related Experiment Video
Updated: Mar 9, 2026
Measuring 3D In-vivo Shoulder Kinematics using Biplanar Videoradiography
Published on: March 12, 2021
Association Between Cardiovascular Disease Risk Factors and Rotator Cuff Tendinopathy: A Cross-Sectional Study
Kara Arnold Applegate1, Matthew S Thiese, Andrew S Merryweather
1Rocky Mountain Center for Occupational and Environmental Health (RMCOEH) (Ms Applegate, Drs Thiese, Wood, Hegmann), Department of Mechanical Engineering, University of Utah, Salt Lake City, Utah (Dr Merryweather), Center for Ergonomics, University of Wisconsin-Milwaukee (Drs Kapellusch, Foster, Garg), Veterans Administration Medical Center, Milwaukee, Wisconsin (Dr Drury), and Division of Physical Medicine and Rehabilitation, University of Utah, Salt Lake City, Utah (Mr Kendall).
Insights
Cardiovascular disease risk factors are strongly linked to shoulder pain and rotator cuff issues. Managing these risk factors may help reduce the incidence of these common musculoskeletal disorders.
Area of Science:
- Orthopedics
- Cardiology
- Epidemiology
Background:
- Emerging evidence suggests a connection between cardiovascular disease (CVD) risk factors and musculoskeletal conditions.
- Glenohumeral joint pain and rotator cuff tendinopathy are prevalent musculoskeletal disorders.
Purpose of the Study:
- To investigate the association between cardiovascular disease risk factors and glenohumeral joint pain.
- To examine the relationship between cardiovascular disease risk factors and rotator cuff tendinopathy.
Main Methods:
- Utilized data from 1226 participants in the WISTAH hand study.
- Assessed associations between Framingham Heart Study cardiovascular disease risk factors and shoulder health outcomes.
Main Results:
- A significant association was found between cardiovascular disease risk scores and both glenohumeral joint pain (OR 4.55) and rotator cuff tendinopathy (OR 5.97).
- A dose-response trend indicated increasing risk with higher cardiovascular disease risk scores.
- Individual cardiovascular disease risk factors were independently associated with both shoulder conditions.
Conclusions:
- Cardiovascular disease risk factors show a strong correlation with glenohumeral joint pain and an even stronger correlation with rotator cuff tendinopathy.
- These findings suggest a potentially modifiable disease mechanism linking cardiovascular health and shoulder disorders.
Objective:
Recent evidence has found potential associations between cardiovascular disease (CVD) risk factors and common musculoskeletal disorders. We evaluated possible associations between risk factors and both glenohumeral joint pain and rotator cuff tendinopathy.
Methods:
Data from WISTAH hand study participants (n = 1226) were assessed for associations between Framingham Heart Study CVD risk factors and both health outcomes.
Results:
A strong association was observed between CVD risk scores and both glenohumeral joint pain and rotator cuff tendinopathy. Peak odds ratios (ORs) of the adjusted models were 4.55 [95% confidence interval (95% CI) 1.97 to 10.31] and 5.97 (95% CI 2.12 to 16.83), respectively. The results show a dose-response trend of increasing risk.
Conclusions:
Individual risk factors were associated with both outcomes. Combined, CVD risk factors demonstrated a strong correlation with glenohumeral joint pain and an even stronger correlation with rotator cuff tendinopathy. Results suggest a potentially modifiable disease mechanism.
More Related Videos
07:22Arthroscopic Management of Massive Irreparable Rotator Cuff Tears: Whole Rotator Cable Reconstruction Using Proximal Biceps Tendon Autograft
Published on: June 6, 2025
07:10Modified Long Head of Biceps Tendon Rerouting and Fixation as Partial Capsular Reconstruction for Massive Irreparable Rotator Cuff Tears
Published on: March 6, 2026
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
01:27Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...