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Updated: Mar 9, 2026

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis
Published on: June 10, 2022
Prenatal intestinal volvulus: look for cystic fibrosis
Taieb Chouikh1, Nicolas Mottet2, Christelle Cabrol3
1Department of Chirurgie Pédiatrique, Centre Hospitalier Regional Universitaire de Besançon, Besançon, France.
Abstract:
Intestinal volvulus is a life-threatening emergency requiring prompt surgical management. Prenatal intestinal volvulus is rare, and most are secondary to intestinal atresia, mesenteric defect or without any underlying cause. Cystic fibrosis (CF) is known to cause digestive tract disorders. After birth, 10-15% of newborns with CF may develop intestinal obstruction within a few days of birth because of meconial ileus.1 This obstruction is a result of dehydrated thickened meconium obstructing the intestinal lumen. We report two cases of fetuses with prenatal diagnosis of segmental volvulus in whom CF was diagnosed.
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