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Progress towards Rapid Detection of Measles Vaccine Strains: a Tool To Inform Public Health Interventions
1Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California, USA jill.hacker@cdph.ca.gov.
Abstract:
Rapid differentiation of vaccine from wild-type strains in suspect measles cases is a valuable epidemiological tool that informs the public health response to this highly infectious disease. Few public health laboratories sequence measles virus-positive specimens to determine genotype, and the vaccine-specific real-time reverse transcriptase PCR (rRT-PCR) assay described by F. Roy et al. (J. Clin. Microbiol. 55:735-743, 2017, https://doi.org/10.1128/JCM.01879-16) offers a rapid, easily adoptable method to identify measles vaccine strains in suspect cases.
