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Cytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus Infection

Yuan Tian1, Alessandro Sette1, Daniela Weiskopf1

  • 1Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology , La Jolla, CA , USA.

Frontiers in Immunology
|December 23, 2016
PubMed
Summary

Cytotoxic CD4 T cells are crucial for controlling dengue virus (DENV) infection. Understanding their function may lead to new strategies for preventing and treating severe dengue disease.

Keywords:
CD4 T cellscytotoxicitydengue virusprotectionvaccines

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