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Updated: Mar 9, 2026

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
Published on: February 17, 2023
[Periodontal Ligament Injection - An important alternative to conventional techniques?]
Jan Samuel Schenkel1, Heinz-Theo Lübbers, Philipp Metzler
1Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Zentrum für Zahnmedizin der Universität Zürich, Zürich, Switzerland.
Abstract:
Reliable analgesia can nowadays be achieved with several techniques and different anesthetic solutions, but side effects may be encountered. Severe and potentially fatal cardiovascular reactions can be the result of an intravascular injection. An easy to use, effective and safe alternative is the periodontal ligament injection. Nerve damage or cardiovascular side effects are not to be expected. This type of anesthesia can be of advantage for many dental procedures. With new devices like the computer-controlled local anesthetic delivery system, the periodontal ligament injection is a convenient way of local anesthesia for both patient and dentist.

