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[Composition of the intestinal microflora in children with hypotrophy]
Insights
Children with hypotrophy often have intestinal dysbacteriosis. Bacterial drug treatment can restore intestinal microflora balance in these pediatric patients.
Area of Science:
- Pediatrics
- Microbiology
- Gastroenterology
Context:
- Investigated intestinal microflora in 120 children (1 month to 2 years) with hypotrophy.
- Identified widespread intestinal dysbacteriosis in the majority of participants.
- Explored correlations between dysbiosis severity and etiological factors.
Purpose:
- To analyze the intestinal microflora in children with hypotrophy.
- To determine the relationship between dysbiosis and factors like nutrition, feeding type, and treatment.
- To evaluate the efficacy of bacterial drug inclusion in treating hypotrophy-associated dysbiosis.
Summary:
- Dysbiosis was prevalent in children with hypotrophy, varying in severity.
- Dysbiosis correlated with etiological factors, hypotrophy severity, feeding type, and treatment.
- Treatment involving bacterial drugs normalized or improved intestinal microflora in affected children.
Impact:
- Highlights the link between hypotrophy, dysbiosis, and potential contributing factors such as antibiotic use and inadequate nutrition.
- Demonstrates the therapeutic potential of bacterial drugs in restoring gut health in pediatric hypotrophy.
- Suggests dysbiosis in hypotrophy may result from inappropriate antibiotic therapy, poor feeding, and reduced immunity.
Abstract:
The intestinal microflora was investigated in 120 children aged 1 month to 2 years with different forms of hypotrophy. The majority of the children demonstrated an impairment of intestinal biocenosis manifesting by dysbacteriosis of different gravity. The relationship was discovered between the depth of the dysbiotic abnormalities and the underlying etiological factor that promoted the development of the chronic nutrition distress, hypotrophy gravity, the type of feeding, and treatment. The treatment of hypotrophy with bacterial drug inclusion made the children's intestinal microflora return to normal or appreciably improved it. The dysbiotic abnormalities in children with hypotrophy should be regarded as the result of the long-term use of antibacterial therapy (not justified in all the cases) in this patients' group, of inadequate feeding, and a considerable decrease of the body resistance.