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Published on: May 12, 2023
Anaphylactic reaction secondary to topical preoperative moxifloxacin
Michael A Ullman1, Kirsten J Midgley1, Jocelyn Kim1
1From the Department of Ophthalmology (M.A. Ullman, Midgley, Kim), MedStar Washington Hospital Center, and the Department of Ophthalmology (M.A.Ullman, Midgley, Kim), MedStar Georgetown University Hospital, Washington, DC; Ullman Eye Consultants (S. Ullman), Pensacola, Florida, USA.
Abstract:
We report a case of anaphylactic shock following topical administration of moxifloxacin for endophthalmitis prophylaxis prior to cataract surgery. Immunoglobulin E (IgE) serology and IgE skin testing confirmed the anaphylactic etiology. Phacoemulsification with posterior chamber intraocular lens implantation was later performed with identical preoperative preparation except for the exclusion of moxifloxacin; no anaphylactic response occurred. To our knowledge, this is the first report of an anaphylactic response to topical moxifloxacin.
Financial Disclosure:
None of the authors has a financial or proprietary interest in any material or method mentioned.
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