Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypodermis01:02

Hypodermis

8.3K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
8.3K
Loose Connective Tissue01:26

Loose Connective Tissue

11.0K
Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...
11.0K
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

27.3K
Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis...
27.3K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

4.3K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
4.3K
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

1.8K
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Questions of the future in aging and longevity research at the GIMM Festival.

Nature aging·2026
Same author

Cell motility influences microfluidics capturing in scRNA-seq.

Open research Europe·2026
Same author

Flow cytometry-based evaluation of hepatic infection by non-fluorescent Plasmodium parasites.

International journal for parasitology·2026
Same author

Pathways of mRNA decay in trypanosomes.

Current opinion in microbiology·2026
Same author

Classification of Trypanosoma brucei mammalian life cycle stages using Deep Learning Algorithms.

PLoS neglected tropical diseases·2025
Same author

CSP ubiquitylation favours Plasmodium berghei survival during early liver stage infection.

Scientific reports·2025

Related Experiment Video

Updated: Mar 9, 2026

Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

42.3K

Adipose Tissue: A Safe Haven for Parasites?

Herbert B Tanowitz1, Philipp E Scherer2, Maria M Mota3

  • 1Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA.

Trends in Parasitology
|December 24, 2016
PubMed
Summary

Adipose tissue (AT) is a key regulator of energy and immunity. Three parasites, Trypanosoma cruzi, Trypanosoma brucei, and Plasmodium spp., uniquely associate with AT, impacting disease pathogenesis and treatment.

Keywords:
Trypanosomaadipocyteadipose tissuefatlipidmalariapathogen

More Related Videos

Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

45.6K
Isolation of Adipose Tissue Immune Cells
07:09

Isolation of Adipose Tissue Immune Cells

Published on: May 22, 2013

37.2K

Related Experiment Videos

Last Updated: Mar 9, 2026

Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

42.3K
Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

45.6K
Isolation of Adipose Tissue Immune Cells
07:09

Isolation of Adipose Tissue Immune Cells

Published on: May 22, 2013

37.2K

Area of Science:

  • Parasitology
  • Immunology
  • Metabolic disease

Background:

  • Adipose tissue (AT) is recognized for its role in energy homeostasis and immunity.
  • Three distinct parasite species interact with AT during their life cycles.

Purpose of the Study:

  • To explore the unique adaptations of Trypanosoma cruzi, Trypanosoma brucei, and Plasmodium spp. within adipose tissue.
  • To discuss the implications of these interactions for disease development and treatment.

Main Methods:

  • Review of existing literature on parasite-adipose tissue interactions.
  • Comparative analysis of parasite localization and adaptation within AT.

Main Results:

  • Trypanosoma cruzi resides within adipocytes.
  • Trypanosoma brucei inhabits interstitial spaces between adipocytes.
  • Plasmodium spp. infect red blood cells that may adhere to AT vasculature.

Conclusions:

  • Parasite adaptations to AT influence pathogenesis, clinical presentation, and therapeutic strategies.
  • Understanding these interactions is crucial for managing Chagas disease, African sleeping sickness, and malaria.