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The American Urological Association Symptom Index for Benign Prostatic Hyperplasia
Michael J Barry1, Floyd J Fowler1, Michael P O'leary1
1Medical Practices Evaluation Center, Massachusetts General Hospital and Harvard Medical School, Center for Survey Research, University of Massachusetts, Boston, Massachusetts; Department of Urology, Tufts University School of Medicine, Boston, Massachusetts; Department of Urology, University of Wisconsin at Madison, Madison, Wisconsin; Department of Urology, Johns Hopkins University, Baltimore, Maryland; Department of Urology, University of Rochester Medical Center, Rochester, New York; Section of Urology, The University of Kansas Medical Center, Kansas City, Kansas, and the American Urological Association.
Abstract:
A symptom index for benign prostatic hyperplasia (BPH) was developed and validated by a multidisciplinary measurement committee of the American Urological Association (AUA). Validation studies were conducted involving a total of 210 BPH patients and 108 control subjects. The final AUA symptom index includes 7 questions covering frequency, nocturia, weak urinary stream, hesitancy, intermittence, incomplete emptying and urgency. On revalidation, the index was internally consistent (Cronbach's α = 0.86) and the score generated had excellent test-retest reliability (r = 0.92). Scores were highly correlated with subjects' global ratings of the magnitude of their urinary problem (r = 0.65 to 0.72) and powerfully discriminated between BPH and control subjects (receiver operating characteristic area 0.85). Finally, the index was sensitive to change, with preoperative scores decreasing from a mean of 17.6 to 7.1 by 4 weeks after prostatectomy (p <0.001). The AUA symptom index is clinically sensible, reliable, valid and responsive. It is practical for use in practice and for inclusion in research protocols.
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