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Posner-Schlossman syndrome.

Roly Megaw1, Pankaj Kumar Agarwal2

  • 1Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom; Princess Alexandra Eye Pavilion, Edinburgh, United Kingdom.

Survey of Ophthalmology
|December 26, 2016
PubMed
Summary
This summary is machine-generated.

Posner-Schlossman syndrome, a rare unilateral eye condition, involves recurrent uveitis and high intraocular pressure, potentially leading to glaucoma. It is linked to cytomegalovirus infection and primarily affects middle-aged men.

Keywords:
Posner-Schlossmancytomegalovirusglaucomaglaucomacyclitic crisisiridocyclitisuveitis

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Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Posner-Schlossman syndrome (PSS), or glaucomatocyclitic crisis, is a unilateral ocular condition.
  • Characterized by recurrent nongranulomatous anterior uveitis and elevated intraocular pressure (IOP).
  • Can lead to chronic secondary glaucoma.

Purpose of the Study:

  • To review the current understanding of Posner-Schlossman syndrome.
  • To discuss its pathophysiology, diagnosis, and management.

Main Methods:

  • Clinical diagnosis is primary.
  • Aqueous and blood sampling assist in identifying infectious causes.
  • Review of existing literature on pathophysiology and treatment.

Main Results:

  • PSS is likely caused by recurrent cytomegalovirus infection.
  • Predominantly affects middle-aged males.
  • Diagnosis relies on clinical presentation and laboratory tests.

Conclusions:

  • Successful management often involves topical treatments.
  • Systemic therapy and surgical intervention may be necessary in some cases.
  • Understanding PSS pathophysiology is crucial for effective treatment.