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Studying the Interaction of Magainin 2 and Cecropin A with E. coli Bacterial Cells Using Circular Dichroism
Concetta Avitabile1, Luca Domenico D'Andrea1, Alessandra Romanelli2,3
1Institute of Biostructure and Bioimaging CNR, via Mezzocannnone 16, 80134, Naples, Italy.
Methods in Molecular Biology (Clifton, N.J.)
|December 26, 2016
Abstract:
The potential of antimicrobial peptides (AMPs) as an effective therapeutic alternative to classic and current antibiotics has encouraged studies to understand how they interact with the bacterial membrane. Here we describe how to detect, by circular dichroism (CD), the secondary structures of two antimicrobial peptides, magainin 2 and cecropin A, in the presence of E. coli bacterial cells.

