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Oxalate: effect on calcium absorbability.

R P Heaney1, C M Weaver

  • 1Creighton University, Omaha, NE 68178.

The American Journal of Clinical Nutrition
|October 1, 1989
PubMed
Summary
This summary is machine-generated.

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Calcium absorption from calcium oxalate was measured in women. Calcium oxalate absorption was higher than previously found for spinach calcium, and oxalate did not interfere with calcium absorption from milk.

Area of Science:

  • Nutritional Science
  • Human Physiology
  • Mineral Metabolism

Background:

  • Dietary calcium absorption is influenced by various food components.
  • Oxalate is known to bind calcium, potentially reducing its bioavailability.
  • Understanding calcium absorption from different sources is crucial for dietary recommendations.

Purpose of the Study:

  • To quantify calcium absorption from calcium oxalate in normal women.
  • To compare calcium absorption from calcium oxalate with that from milk.
  • To investigate the effect of ingesting calcium oxalate and milk together on calcium absorption.

Main Methods:

  • Intrinsically labeled calcium oxalate and milk were used.
  • Calcium absorption was measured in 18 normal women.

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  • Test substances were ingested both separately and together in meals.

    • Main Results:

    • Fractional calcium absorption from calcium oxalate averaged 0.100 alone and 0.140 with milk.
    • Calcium absorption from milk was significantly higher (0.358).
    • Calcium oxalate absorbability was higher than previously reported for spinach calcium; no interference was observed when consumed with milk.

    Conclusions:

    • Calcium absorption from calcium oxalate is lower than from milk but significant.
    • Dietary oxalate does not appear to inhibit calcium absorption from milk when consumed together.
    • These findings contribute to understanding calcium bioavailability from plant-based sources.