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Protein and Peptide Biopharmaceuticals: An Overview
Dominic Agyei, Ishtiaq Ahmed, Zain Akram
1Department of Chemical Engineering, Curtin University, Malaysia.
Protein and Peptide Letters
|December 27, 2016
Summary
Bioactive proteins and peptides are emerging as key therapeutic molecules. This review covers their synthesis, applications, and the factors influencing their use in medicine.
Area of Science:
- Biotechnology
- Pharmacology
- Drug Development
Background:
- Bioactive proteins and peptides are recognized for their diverse biological properties and therapeutic potential.
- The development and approval of protein and peptide-based therapeutics by regulatory bodies like the US Food and Drug Administration (FDA) are increasing.
- These molecules represent a growing sector in pharmaceutical development.
Purpose of the Study:
- To review the current landscape of protein and peptide biopharmaceutical synthesis.
- To highlight the methodologies employed in creating these therapeutic agents.
- To identify key drivers and challenges in the commercial exploitation of protein and peptide therapeutics.
Main Methods:
- Literature review of current scientific publications and regulatory data.
- Analysis of synthesis methodologies for protein and peptide biopharmaceuticals.
- Examination of market trends and regulatory approvals.
Main Results:
- Protein and peptide therapeutics are gaining significant traction in the pharmaceutical market.
- Various synthesis techniques are available, each with specific advantages and limitations.
- Market growth is influenced by factors such as therapeutic efficacy, manufacturing costs, and regulatory pathways.
Conclusions:
- Protein and peptide biopharmaceuticals represent a significant and expanding area of therapeutic innovation.
- Understanding synthesis methods and market dynamics is crucial for successful drug development.
- Continued research and development are expected to overcome existing limitations and expand therapeutic applications.
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