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Related Experiment Videos

Hepatitis and hematemesis complicating nicotinic acid use.

G Ferenchick1, D Rovner

  • 1Department of Medicine, Michigan State University, East Lansing 48824.

The American Journal of the Medical Sciences
|September 1, 1989
PubMed
Summary

High doses of nicotinic acid (vitamin B3) can cause serious side effects. This case report details a young man who developed hematemesis and hepatitis after taking 6g daily.

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Area of Science:

  • Biochemistry
  • Hepatology
  • Clinical Medicine

Background:

  • Nicotinic acid, a water-soluble B vitamin, is effective for hypercholesterolemia.
  • Therapeutic use has shown survival benefits in cardiovascular trials.
  • High doses are associated with significant side effects.