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Cost of persistent asthma in Italy
Roberto W Dal Negro1, Chiara Distante2, Luca Bonadiman3
1National Centre for Respiratory Pharmacoeconomics and Pharmacoepidemiology, Verona, Italy.
Multidisciplinary Respiratory Medicine
|December 27, 2016
Summary
This study updated the cost of persistent asthma in Italy, finding that while overall costs increased slightly due to longer treatment durations, key healthcare expenditures like hospitalizations decreased, indicating improved asthma management.
Area of Science:
- Pulmonary Medicine
- Health Economics
Background:
- Asthma represents a significant public health burden, impacting patient quality of life and incurring substantial societal costs.
- Previous studies, such as SIRIO in 2007, estimated mean annual costs per patient in Italy.
- This research aimed to provide an updated cost analysis for persistent asthma patients in Italy.
Purpose of the Study:
- To update the economic burden of persistent asthma in Italy.
- To analyze changes in healthcare resource utilization and clinical outcomes in asthma patients.
- To inform healthcare policy and resource allocation for asthma management.
Main Methods:
- An observational, retrospective, bottom-up analysis was conducted using data from Verona, Italy (June 2013-December 2015).
- Patient data were collected for 12 months pre-enrollment and 12 months during follow-up.
- Clinical outcomes (FEV1%, relapses) and healthcare resource use (hospitalizations, visits, medications, indirect costs) were recorded.
Main Results:
- The cohort included 817 persistent asthma patients, with a mean age of 49 years and 69% having comorbidities.
- Following 12 months of follow-up, forced expiratory volume in 1 second (FEV1%) significantly improved (+6.31%), and the number of relapses decreased (-0.46 per patient/year).
- The total annual cost per patient was €1,183.14 pre-enrollment and €1,290.89 post-enrollment, an increase driven by longer therapeutic strategies, though hospitalization and medication costs decreased.
Conclusions:
- Periodic cost analysis is crucial for monitoring asthma outcomes and expenditure trends.
- Updated cost data aids in planning effective prevention and intervention strategies to optimize healthcare resource use.
- Appropriate pharmacological strategies are vital for minimizing asthma morbidity and its socio-economic impact.
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