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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
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Evolution of design considerations in complex craniofacial reconstruction using patient-specific implants.

Sean Peel1, Satyajeet Bhatia2, Dominic Eggbeer1

  • 11 PDR - International Centre for Design & Research, Cardiff Metropolitan University, Cardiff, UK.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
|December 27, 2016
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Summary

This study introduces a design considerations framework for patient-specific devices created using computer-aided design, computer-aided manufacturing, and additive manufacturing, addressing a gap in current clinical practice and guiding future research.

Keywords:
Implants/prostheticsadditive manufacturingcomputer-aided designcomputer-assisted surgeryorthopaedic materialssurgical guidesthree-dimensional printing

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Area of Science:

  • Biomedical Engineering
  • Medical Device Design
  • Digital Manufacturing

Background:

  • Patient-specific devices (PSDs) manufactured using computer-aided design (CAD), computer-aided manufacturing (CAM), and additive manufacturing (AM) offer significant clinical benefits.
  • Despite proven advantages, routine adoption, especially within the UK National Health Service, remains limited due to cost, material uncertainty, and lack of long-term data.

Purpose of the Study:

  • To identify and synthesize design rules and key specification considerations for complex CAD/CAM/AM patient-specific devices.
  • To address a critical knowledge gap hindering the widespread clinical implementation of these advanced medical technologies.

Main Methods:

  • A comprehensive literature review was conducted to extract existing design considerations.
  • Five craniofacial patient case studies involving virtual surgical planning and the fabrication of guides and implants were analyzed.
  • New design considerations were derived from clinical evaluations of these case studies.

Main Results:

  • Nineteen recurring design considerations were identified from the literature review.
  • Nine novel design considerations were extracted from the clinical case studies.
  • A synthesized design considerations framework was developed to aid clinicians and engineers.

Conclusions:

  • The developed framework provides essential guidance for the design and prescription of patient-specific devices.
  • This research bridges the gap between advanced manufacturing capabilities and clinical application, promoting better patient outcomes.
  • Further research is recommended to validate and expand upon the proposed design considerations.