[Immunologic aspects of the macrophages in the milk of preterm mothers]

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Bone Marrow-derived Macrophage Production
07:06

Bone Marrow-derived Macrophage Production

Published on: November 22, 2013

M C Rodríguez Rodríguez1, J L Subiza Garrido-Lestache, P Mateos Burguillo

  • 1Servicio de Pediatría, Hospital Universitario San Carlos, Madrid.

Anales Espanoles De Pediatria
|July 1, 1989
PubMed

Number and function of milk macrophages from 25 healthy mothers delivering preterm (PHMMo) (mean gestational age 33 weeks) were compared with those obtained from 74 mothers with term delivery (THMMo). The average concentration of MMø in colostrum did not differ among both sources: 0.55 x 10(6)/ml (PHMMo) and 0.42 x 10(6)/ml (THMMo). The mean phagocytic index of PHMMo (3.35 yeasts/cell) and THMMo (3.40 yeasts/cell) was similar (p greater than 0.05); both cell types were significantly higher than control monocytes (CMo) (1.95 yeasts/cell) (p less than 0.001). The mean chemotactic function of PHMMo (11.58 cells/field) was significantly greater than THMMo (2.75 cells/field) (p less than 0.001). However, both milk cells showed lower chemotaxis than CMo (32.63 cells/field) (p less than 0.001).

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