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Updated: Mar 9, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Taxonomy for colorectal cancer screening promotion: Lessons from recent randomized controlled trials
Paul Ritvo1, Ronald E Myers2, Mardie Serenity3
1York University, Kinesiology and Health Science, 4700 Keele St., Toronto, ON CAN M3J 1P3, Canada; Ontario Cancer Institute, Division of Epidemiology and Biostatistics, 600 University Ave., Toronto, ON CAN M5G2C4, Canada.
Objective:
To derive a taxonomy for colorectal cancer screening that advances Randomized Controlled Trials (RCTs) and screening uptake.
Design:
Detailed publication review, multiple interviews with principal investigators (PIs) and collaboration with PIs as co-authors produced a CRCS intervention taxonomy. Semi-structured interview questions with PIs (Drs. Inadomi, Myers, Green, Gupta, Jerant and Ritvo) yielded details about trial conduct. Interview comparisons led to an iterative process informing serial interviews until a consensus was obtained on final taxonomy structure.
Results:
These taxonomy headings (Engagement Sponsor, Population Targeted, Alternative Screening Tests, Delivery Methods, and Support for Test Performance (EPADS)) were used to compare studies. Exemplary insights emphasized: 1) direct test delivery to patients; 2) linguistic-ethnic matching of staff to minority subjects; and 3) authorization of navigators to schedule or refer for colonoscopies and/or distribute stool blood tests during screening promotion.
Conclusion:
PIs of key RCTs (2012-2015) derived a CRCS taxonomy useful in detailed examination of CRCS promotion and design of future RCTs.
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