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Updated: Mar 9, 2026

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
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Refractive changes following corrective surgery for thyroid-related orbitopathy.

Michael Kinori1, Kyle J Godfrey1, Katherine M Whipple2

  • 1Division of Pediatric Ophthalmology and Eye Alignment Disorders at the Ratner Childrens Eye Center, Department of Ophthalmology, University of California-San Diego, La Jolla, California.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|December 28, 2016
PubMed
Summary

Thyroid-related orbitopathy (TRO) surgery can cause refractive changes. This study found significant shifts in cylinder, axis, and spherical equivalent after strabismus surgery in TRO patients.

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Area of Science:

  • Ophthalmology
  • Endocrinology
  • Graves' disease research

Background:

  • Thyroid-related orbitopathy (TRO), a Graves' disease manifestation, involves orbital tissue changes.
  • These changes can alter globe shape and induce refractive errors.
  • Surgical interventions for TRO may further impact vision and refractive status.

Purpose of the Study:

  • To investigate refractive changes in patients with TRO undergoing strabismus surgery.
  • To assess the impact of orbital decompression combined with strabismus surgery on refractive outcomes.

Main Methods:

  • Manifest refraction was performed preoperatively and postoperatively.
  • 33 patients with TRO who underwent strabismus surgery (with or without orbital decompression) were included.
  • Statistical analysis was used to evaluate refractive shifts.

Main Results:

  • Statistically significant postoperative changes were observed in refractive cylinder.
  • Significant shifts in refractive axis were documented postoperatively.
  • Postoperative changes in spherical equivalent were also statistically significant.

Conclusions:

  • Strabismus surgery in patients with TRO leads to significant refractive alterations.
  • Ophthalmologists should consider these refractive shifts when managing TRO patients post-surgery.
  • Further research may explore the mechanisms behind these refractive changes.