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Updated: Mar 9, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery aneurysms detected by computed tomography coronary angiography
Ernesto Forte1, Marco Aiello1, Marianna Inglese1
1IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy.
Insights
Computed tomography coronary angiography (CTCA) offers a non-invasive method to detect coronary artery aneurysms (CAAs), accurately assessing their prevalence and features, even with intraluminal thrombi. This technique overcomes limitations of invasive coronary angiography.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Coronary artery aneurysms (CAAs) are localized dilations of coronary arteries, often incidentally found.
- Invasive coronary angiography (ICA) is standard but may underestimate aneurysm size due to thrombi.
- Computed tomography coronary angiography (CTCA) offers superior visualization of coronary lumen and intraluminal thrombi.
Purpose of the Study:
- To evaluate the prevalence and characteristics of CAAs using CTCA.
- To compare CTCA findings with invasive coronary angiography (ICA) limitations.
- To assess CTCA's ability to visualize aneurysms with intraluminal thrombi.
Main Methods:
- Retrospective review of 390 CTCA scans.
- Identification of 9 patients with CAAs (aneurysmal group) and matched controls.
- Comparison of clinical variables and imaging findings between groups.
Main Results:
- CAAs prevalence was 2.31% in the studied population.
- 15 CAAs were detected, predominantly in the right coronary artery (RCA).
- CTCA revealed aneurysmal thrombosis in 66.7% and associated stenoses in 55.5% of cases.
Conclusions:
- CTCA enables non-invasive estimation of CAA prevalence and detailed characterization.
- CTCA overcomes ICA limitations, providing precise analysis of aneurysms, including those with thrombi.
- CTCA enhances the understanding of coronary anatomy in patients with CAAs.
Aims:
Coronary artery aneurysms (CAAs) are incidentally revealed by coronary angiography and consist in a localized dilation of a coronary artery. Although invasive coronary angiography (ICA) is the gold standard imaging technique, it can lead to the underestimation of CAAs diameter in presence of parietal thrombi. Computed tomography coronary angiography (CTCA) is a very sensitive tool in CAAs detection and provides a clear visualization of coronary lumen highlighting intraluminal thrombi.
Methods And Results:
We retrospectively reviewed 390 CTCA performed at our institution, 9 patients (6 men, 3 women) resulted affected by CAAs and represented the aneurysmal group (A group). Matched controls were identified among the non-aneurysmal patients with healthy coronaries to CTCA (NAH group). Clinical variables and imaging findings were compared and correlated. CAAs prevalence in our population was 2.31%. 15 CAAs were detected, mainly on the right coronary artery (RCA) (9 aneurysms) followed by the left anterior descending coronary artery (LAD) (three aneurysms) and the left circumflex coronary artery (CX) (three aneurysms). In six patients (66.7%) CTCA displayed an aneurysmal thrombosis and in 5 patients (55.5%) CAAs were associated to coronary artery stenoses. A statistically significant difference was found between the diameters of coronary vessels measured in healthy segments in A and NAH group.
Conclusions:
CTCA has led to a non-invasive estimation of CAAs prevalence and characterization of aneurysmal features and coronary anatomy. Overcoming ICA limitations, CTCA has provided a fine analysis of the aneurysms, also in presence of intraluminal thrombi.
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