Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal animal health monitoring in extensive livestock production systems.

Frontiers in veterinary science·2026
Same author

Upcycling Coir Fiber into Polydopamine-Enabled Adsorbents for Efficient Cu(II)/Cd(II) Removal and Effluent Safety.

Materials (Basel, Switzerland)·2026
Same author

Integrating Network Pharmacology and In Vitro 3D Cardiac Organoid Model Validation to Investigate the Action Mechanism of Shenfu Xiangshao Decoction on Heart Failure.

Journal of cardiovascular pharmacology·2026
Same author

Enlarged Perivascular Spaces and Modifiable Vascular Risk Factors: Cross-Sectional and Longitudinal Analysis in the UK Biobank Cohort.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2025
Same author

Multiscale attention generative adversarial networks for lesion synthesis in chest X-ray images.

Scientific reports·2025
Same author

The Motion Picture: Leveraging Movement to Enhance AI Object Detection in Ecology.

Ecology and evolution·2025

Related Experiment Video

Updated: Mar 9, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K

HEDD: the human epigenetic drug database.

Yunfeng Qi1, Dadong Wang2, Daying Wang3

  • 1Department of Bioscience, School of Life Science, Jilin Normal University, Siping, China qiyunfeng911@outlook.com.

Database : the Journal of Biological Databases and Curation
|December 28, 2016
PubMed
Summary
This summary is machine-generated.

A new Human Epigenetic Drug Database (HEDD) integrates diverse experimental data for epigenetic drugs. This resource aids drug discovery and repurposing by enabling flexible queries on drug, target, disease, and high-throughput datasets.

More Related Videos

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.7K
Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes
10:26

Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes

Published on: January 16, 2015

8.9K

Related Experiment Videos

Last Updated: Mar 9, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.7K
Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes
10:26

Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes

Published on: January 16, 2015

8.9K

Area of Science:

  • Pharmacology
  • Bioinformatics
  • Genomics

Background:

  • Epigenetic drugs target histone and DNA modifications, crucial in disease.
  • Experimental data (gene expression, structures, binding constants) are available but fragmented.
  • Existing databases lack comprehensive high-throughput data and flexible querying.

Purpose of the Study:

  • To develop a comprehensive database for human epigenetic drugs.
  • To integrate diverse experimental and manually curated epigenetic drug datasets.
  • To facilitate data extraction and flexible querying for drug discovery and repurposing.

Main Methods:

  • Developed the Human Epigenetic Drug Database (HEDD).
  • Incorporated five key datasets: drug, target, disease, high-throughput, and complex.
  • Implemented flexible search options for unlimited condition queries using drug names, diseases, and experiment types.

Main Results:

  • HEDD provides a centralized repository for human epigenetic drug information.
  • The database integrates high-throughput datasets, a gap in previous resources.
  • Flexible querying capabilities enhance data accessibility and utility.

Conclusions:

  • HEDD significantly enhances the accessibility of human epigenetic drug data.
  • The database supports efficient data mining for epigenetic drug discovery and repurposing.
  • HEDD serves as a valuable resource for researchers in the field of epigenetics and drug development.