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Novel Process for 3D Printing Decellularized Matrices
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Designing Biomaterials for 3D Printing.

Murat Guvendiren1, Joseph Molde1, Rosane M D Soares2

  • 1New Jersey Center for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, New Jersey 08854, United States.

ACS Biomaterials Science & Engineering
|December 28, 2016
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing offers patient-specific tissue engineering solutions. Advances in biomaterial inks are crucial for overcoming limitations in fabricating complex, functional scaffolds and devices.

Keywords:
additive manufacturingceramichydrogelpolymersrapid prototypingtissue engineering

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Additive Manufacturing

Background:

  • Three-dimensional (3D) printing is a key technology for fabricating patient-specific scaffolds and devices in tissue engineering.
  • Its advantages include high structural complexity, rapid on-demand fabrication, and low cost.
  • A significant challenge is the limited diversity of available "biomaterial inks".

Purpose of the Study:

  • This review highlights recent advances in biomaterial ink development for 3D printing.
  • It discusses design considerations for overcoming processing limitations.
  • An overview of 3D printing technologies focusing on ink parameters is provided.

Main Methods:

  • Literature review of biomaterial ink development for 3D printing.
  • Analysis of biomaterial processing challenges.
  • Overview of relevant 3D printing technologies.

Main Results:

  • A wide range of biomaterial inks (polymers, ceramics, hydrogels, composites) have been developed.
  • Processing these materials into self-supporting devices with tunable properties remains a challenge.
  • Ink properties are critical for printability and final device performance.

Conclusions:

  • Advancements in biomaterial ink development are essential for the widespread adoption of 3D printing in biomanufacturing.
  • Addressing challenges in material processing will enable the creation of sophisticated tissue engineering constructs.
  • Future research should focus on inks with tailored mechanics, degradation, and bioactivity.