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Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis
Published on: December 8, 2023
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Haploidentical hematopoietic cell transplantation for disseminated Ewing sarcoma
Hiroki Yoshihara1, Tadashi Kumamoto2, Rintaro Ono1
1Department of Pediatrics, St Luke's International Hospital, Tokyo, Japan.
Summary
Haploidentical hematopoietic cell transplantation may benefit children with disseminated Ewing sarcoma family of tumors (ESFT). This treatment induced a graft-versus-tumor effect, leading to long-term remission in a young patient despite graft-versus-host disease.
Area of Science:
- Pediatric Oncology
- Hematology
- Immunology
Background:
- Ewing sarcoma family of tumors (ESFT) is a rare bone and soft tissue cancer primarily affecting children and young adults.
- Disseminated or multifocal ESFT presents a significant therapeutic challenge with limited effective treatment options.
- Hematopoietic cell transplantation (HCT) is explored as a strategy to achieve durable remission in refractory or relapsed malignancies.
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