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Updated: Mar 9, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Aortic Root Enlargement or Sutureless Valve Implantation?
Nikolaos G Baikoussis1, Panagiotis Dedeilias1, Michalis Argiriou1
1Evangelismos General Hospital of Athens, Athens, Greece.
Avoiding prosthesis-patient mismatch (PPM) after aortic valve replacement (AVR) is crucial for survival. The sutureless Perceval S bioprosthesis offers a solution for patients with small aortic annuli, optimizing hemodynamic performance and avoiding PPM.
Area of Science:
- Cardiac Surgery
- Cardiovascular Devices
- Prosthetic Heart Valves
Background:
- Aortic valve replacement (AVR) in patients with small aortic annuli presents significant challenges.
- Prosthesis-patient mismatch (PPM) post-AVR, though debated, negatively impacts patient survival and must be prevented.
- Comorbidities in elderly patients with small aortic roots necessitate innovative solutions.
Purpose of the Study:
- To evaluate the efficacy of the Perceval S sutureless bioprosthesis in preventing PPM in patients with small aortic annuli.
- To compare the outcomes of sutureless valve implantation with traditional aortic root enlargement techniques.
- To discuss the future role of aortic root enlargement in the context of sutureless surgical AVR (SAVR) and transcatheter aortic valve implantation (TAVI).
Main Methods:
- Review of existing literature on AVR in small aortic annuli.
- Analysis of hemodynamic performance data for the Perceval S bioprosthesis.
- Discussion of surgical techniques including aortic root enlargement and sutureless valve implantation.
Main Results:
- The Perceval S sutureless bioprosthesis demonstrates reasonable hemodynamic performance.
- This valve effectively avoids PPM by maximizing the aortic orifice area.
- It presents a viable alternative for patients with small aortic roots, especially those with comorbidities.
Conclusions:
- Sutureless bioprostheses like the Perceval S are a promising solution for managing small aortic annuli during AVR.
- These valves help avoid PPM, thereby improving patient outcomes.
- Further research is needed to define the role of aortic root enlargement alongside SAVR and TAVI in this patient population.
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