[New experimental models in microbial ecology]

Peculiar features of dysbiosis development in persons under extreme conditions were studied. It was shown that a number of extreme factors participated in formation of dysbiotic disorders in intestinal microflora. Of paramount importance was the neuro-emotional stress. Lability of bifido- and lactoflora was considered as the starting mechanism in dysbacteriosis under the extreme conditions. In the experimental models with rats SPF and Primates during flights of biosatellites of the Kosmos series the role of indigenous++ microflora in maintaining the microecological homeostasis, as well as the need for development of artificial and controlled intestinal microflora promising in prophylaxis of dysbacteriosis under extreme conditions was shown. The theoretical and experimentally grounded necessity of maintaining constant intestine microbiocenosis was confirmed by the practice of using the system of measures for recovery, stabilization and optimization of microflora in persons under extreme conditions.