Jove
Visualize
Contact Us

Related Experiment Videos

[Patho-anatomic changes in rotaviral gastroenteritis in children].

A V Novikova, E A Smirnov, V M Shebekova

    Arkhiv Patologii
    |January 1, 1989
    PubMed
    Summary

    Two children died from Rotavirus gastroenteritis, confirmed by intestinal tissue analysis. The study details acute enteritis and hepatic fatty infiltration as key indicators of Rotavirus infection in infants.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Assessment of real myocardial energy demand using indirect calorimetry in early postoperative period after cardiac surgery].

    Khirurgiia·2024
    Same author

    [A clinical case of visceral toxocariasis as a cause of eosinophilic polyserositis].

    Terapevticheskii arkhiv·2020
    Same author

    Emotional personality disorders in patients with vibration disease associated with androgen deficiency.

    Meditsina truda i promyshlennaia ekologiia·2018
    Same author

    [Clinical features of pertussis in adults].

    Terapevticheskii arkhiv·2015
    Same author

    [Problems of androgen deficiency associated with somatic diseases in vibration disease patients].

    Meditsina truda i promyshlennaia ekologiia·2014
    Same author

    [Candida infection as a complication in antibiotic therapy].

    Antibiotiki·2014
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Pediatric infectious diseases
    • Gastroenterology
    • Virology

    Background:

    • Rotavirus gastroenteritis is a significant cause of infant mortality globally.
    • Understanding the pathological changes associated with severe Rotavirus infection is crucial for diagnosis and treatment.

    Observation:

    • Two infant deaths were investigated, attributed to Rotavirus gastroenteritis.
    • Autopsies revealed characteristic histopathological changes in the small intestine and liver.

    Findings:

    • Virological, electron microscopic, and immune fluorescence studies confirmed Rotavirus in intestinal tissue.
    • Histological examination showed acute diffuse enteritis with villous abnormalities and inflammatory cell infiltration.
    • Hepatic tissue exhibited central lobular fatty infiltration, indicative of systemic effects.

    Related Experiment Videos

    Implications:

    • These findings underscore the severe pathogenic potential of Rotavirus in infants.
    • The detailed pathological description aids in recognizing Rotavirus-induced enteritis.
    • Influenza was identified as the cause of pneumonia in one case, highlighting potential co-infections.