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Development of a first-generation miniature multiple reference optical coherence tomography imaging device.

Paul M McNamara1, Roshan Dsouza1, Colm O'Riordan2

  • 1National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform, Galway H91 CF50, IrelandbCompact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States.

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This study introduces a miniature Multiple Reference Optical Coherence Tomography (MR-OCT) device for low-cost, compact imaging. The novel design enables extended depth scanning using a miniature voice coil motor, showing potential for various applications.

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Area of Science:

  • Biomedical Optics
  • Optical Engineering
  • Medical Imaging Technology

Background:

  • Optical Coherence Tomography (OCT) is a valuable imaging modality.
  • Traditional OCT systems can be bulky and expensive.
  • Miniaturization is key for broader OCT applications.

Purpose of the Study:

  • To develop and characterize the first iteration of a miniature Multiple Reference Optical Coherence Tomography (MR-OCT) device.
  • To demonstrate the feasibility of compact, low-cost OCT imaging.
  • To explore the potential applications of MR-OCT technology.

Main Methods:

  • Extension of time-domain OCT with a partial mirror in the reference arm.
  • Utilized a miniature voice coil motor for scanning mirror actuation.
  • Employed off-the-shelf miniature optical components and fiber-coupled superluminescent diode.
  • Characterized system performance including spectrum, axial resolution, and signal-to-noise ratio.

Main Results:

  • Successful development of a 40 × 57 mm miniature MR-OCT module.
  • Demonstrated extended, simultaneous depth scanning capabilities.
  • Presented B-scans of static and in vivo samples, validating system performance.
  • Achieved good signal-to-noise ratio and axial resolution.

Conclusions:

  • The developed miniature MR-OCT device is suitable for low-cost, compact imaging.
  • The technology shows significant potential for diverse applications in medical imaging.
  • Further development can lead to even more advanced compact OCT systems.