Cardiovascular Involvement in Behçet Disease: Clinical Implications.

Area of Science:

• Rheumatology
• Cardiology
• Vascular Medicine

Background:

• Behçet disease (BD) is a multisystem vasculitic disorder.
• Classic symptoms include oral/genital ulcers and uveitis.
• Vascular and cardiac involvement are rare but severe complications.

Observation:

• Two male patients from the Mediterranean Basin with BD presented with vascular and cardiac issues.
• One patient was diagnosed with BD early; the other was diagnosed upon cardiovascular manifestation.
• Cardiac involvement in BD, such as intracardiac thrombi, is associated with poor prognosis.

Findings:

• This case series highlights rare vascular and cardiac manifestations in Behçet disease.
• The study emphasizes the importance of recognizing these obscure complications.
• Timely diagnosis and management are critical for improving patient outcomes.

Implications:

• Routine cardiovascular surveillance is recommended for all BD patients, especially in endemic regions.
• Awareness of rare BD complications can prevent misdiagnosis and inappropriate interventions.
• Proactive monitoring may reduce mortality and improve the prognosis for patients with Behçet disease.