Related Experiment Video
Updated: Mar 9, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Urinary tract infections in Romanian patients with diabetes: prevalence, etiology, and risk factors
Teodora Chiţă1, Bogdan Timar1, Delia Muntean1
1Victor Babes University of Medicine and Pharmacy Timisoara; Pius Brinzeu Emergency Hospital.
Aim:
Patients with diabetes mellitus (DM) have an increased risk of infections, especially urinary tract infections (UTIs). The aim of this study was to assess the prevalence and etiology of UTIs and identify the risk factors for their development in patients with DM.
Patients And Methods:
In this retrospective, noninterventional study, the medical records of 2,465 adult patients with DM who were hospitalized in a Diabetes Clinic were reviewed. Data regarding the presence of UTI and possible associated risk factors were collected and their possible relation was analyzed. The study protocol and procedures were approved by the Ethics Committee of Timișoara Emergency Hospital. All data were collected and analyzed using SPSS v.17 statistical software.
Results:
The prevalence of UTIs in patients with DM was 12.0% (297 cases), being higher in females than in males and higher in patients with type 2 DM compared with patients with type 1 DM. In univariate logistic regression analysis, risk factors associated with UTIs were female gender, age, type 2 DM, longer duration of DM, and the presence of chronic kidney disease and coronary artery disease. Multivariate analysis identified age, duration of DM, and metabolic control (hemoglobin A1c levels) as independent risk factors for UTIs. The gram-negative bacilli from the Enterobacteriaceae family were predominant, with Escherichia coli being the most frequent of them (70.4%).
Conclusion:
UTIs are a frequent condition associated with DM. It is necessary to improve the care and the screening of UTIs in patients with DM to prevent the occurrence of possible associated severe renal complications.
Insights
Urinary tract infections (UTIs) are common in patients with diabetes mellitus (DM). Key risk factors include female gender, older age, type 2 DM, longer diabetes duration, and poor metabolic control, necessitating improved screening and care.
Area of Science:
- Endocrinology
- Nephrology
- Infectious Diseases
Background:
- Patients with diabetes mellitus (DM) face a heightened risk of infections, particularly urinary tract infections (UTIs).
- Understanding the prevalence and specific risk factors for UTIs in this population is crucial for effective management.
Purpose of the Study:
- To determine the prevalence and etiological agents of UTIs in patients with DM.
- To identify risk factors associated with UTI development in individuals with diabetes mellitus.
Main Methods:
- A retrospective review of 2,465 adult patients with DM hospitalized in a Diabetes Clinic.
- Analysis of medical records to collect data on UTI presence and associated risk factors.
- Statistical analysis using SPSS v.17, including univariate and multivariate logistic regression.
Main Results:
- The prevalence of UTIs was 12.0% (297 cases), higher in females and patients with type 2 DM.
- Identified risk factors included female gender, age, type 2 DM, longer DM duration, chronic kidney disease, and coronary artery disease.
- Independent risk factors were age, DM duration, and metabolic control (HbA1c); Enterobacteriaceae, especially E. coli, were predominant pathogens.
Conclusions:
- Urinary tract infections are a frequent complication in patients with diabetes mellitus.
- Improved screening and care for UTIs in DM patients are essential to prevent severe renal complications.
Related Concept Videos
Urinary Tract Infection I: Introduction
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection IV: Nursing Management
Nursing Assessment of the Genitourinary System I: Health History
Urinary Tract Calculi I: Introduction

