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Nitric oxide for cancer therapy

Sergio Huerta1

  • 1Department of Surgery, UT Southwestern Medical Center, VA North Texas Health Care System, 4500 S. Lancaster Rd./Surgical Services (112)/Dallas, TX 75216, USA.

Future Science OA
|December 30, 2016
PubMed

Insights

High doses of nitric oxide (NO) show promise in cancer therapy, potentially overcoming resistance to conventional treatments. NO donors are explored as a strategy to enhance antineoplastic compound efficacy.

Area of Science:

  • Oncology
  • Biomedical Science
  • Cancer Therapeutics

Background:

  • Tumor resistance to current cancer treatments is a significant clinical challenge.
  • Nitric oxide (NO) has demonstrated dual roles in cancer, with potential proneoplastic properties.
  • Emerging evidence highlights the therapeutic potential of high-dose NO in cancer treatment.

Conclusions:

  • Nitric oxide (NO) plays a critical role in cancer therapeutics, particularly at high doses.
  • The use of NO donors offers a promising strategy to combat tumor resistance.
  • Further research into NO-based therapies could revolutionize cancer treatment paradigms.
Keywords:
JSKNO donorsNO hybridsdiazeniumdiolates

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