Related Experiment Video
Updated: Mar 9, 2026

09:30
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
20.2K
Gradient nonlinearity calibration and correction for a compact, asymmetric magnetic resonance imaging gradient system
S Tao1,2, J D Trzasko1, J L Gunter1
1Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Physics in Medicine and Biology
|December 30, 2016
Summary
Gradient nonlinearity (GNL) causes geometric distortion in MRI. This study calibrates an asymmetric gradient system, showing that including even-order terms improves spatial accuracy to 0.36 mm.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging Physics
- Image Reconstruction
Background:
- Magnetic Resonance Imaging (MRI) relies on linear spatial encoding gradients.
- Engineering limitations introduce gradient nonlinearity (GNL), causing geometric image distortion.
- Accurate GNL modeling is crucial for correcting image distortions.
Purpose of the Study:
- To characterize and correct GNL in a novel asymmetric MRI gradient system.
- To evaluate the necessity of higher-order and even-order terms for GNL modeling.
- To compare calibration-based GNL coefficients with simulation-based ones.
Main Methods:
- An iterative calibration method using a fiducial phantom was employed.
- Phantom scans were performed across the gradient's spherical volume.
- Spherical harmonic polynomial models up to 10th-order (odd/even and odd-only) were tested.
Main Results:
- Model coefficients for the asymmetric gradient system were successfully estimated.
- GNL correction using 10th-order coefficients reduced residual error to 0.36 mm.
- Even-order terms were essential for accurate GNL modeling; calibrated coefficients outperformed simulation-based ones.
Conclusions:
- Accurate GNL characterization of asymmetric gradient systems requires higher-order and even-order terms.
- The iterative calibration method effectively corrects geometric distortions in MRI.
- This approach achieves spatial accuracy comparable to conventional MRI systems.
Related Concept Videos
NMR Spectrometers: Resolution and Error Correction
1.1K
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
1.1K
Magnetic Resonance Imaging
10.1K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.1K

