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Factors predicting venous thromboembolism after spine surgery
Tao Wang1, Si-Dong Yang, Wen-Zheng Huang
1Department of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang Jizhong Energy Fengfeng Group General Hospital, Handan Shi, Hebei Province Hebei Provincial Key Laboratory of Orthopedic Biomechanics, Shijiazhuang, China.
Medicine
|December 30, 2016
Summary
Venous thromboembolism (VTE) risk after spine surgery is higher in Asian patients, those with pre-operative walking disability, and those with hypertension or diabetes. Lumbar surgery and elastic stocking use were also associated with increased VTE risk.
Area of Science:
- Orthopedics
- Vascular Surgery
- Epidemiology
Background:
- Venous thromboembolism (VTE) is a significant concern following spine surgery for degenerative diseases.
- Existing research on VTE risk factors after spine surgery lacks consensus.
- This meta-analysis aims to identify key predictors of VTE in this patient population.
Purpose of the Study:
- To systematically review and analyze the literature on risk factors for venous thromboembolism (VTE) after spine surgery for degenerative conditions.
- To establish a consensus on the predicted factors contributing to VTE incidence in patients undergoing spinal surgery.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed/MEDLINE, Embase, Cochrane, CNKI, WANFANG).
- Key search terms included "spine," "degeneration," "after surgery," and "venous thromboembolism."
- Data from 12 studies involving 34,597 patients were extracted and analyzed using RevMan 5.3 and STATA 12.0.
Main Results:
- The overall incidence of VTE after spine surgery was 2% (624/34,597 patients).
- Significantly higher VTE incidence was observed in Asian patients (7.5%) compared to Occidental patients (1%).
- Key risk factors identified include pre-operative walking disability (OR=4.80), hypertension (OR=1.59), diabetes (OR=2.12), lumbar surgery site (OR=0.23), and elastic stocking use (OR=11.71).
Conclusions:
- Asian ethnicity, pre-operative walking disability, hypertension, and diabetes are significant risk factors for VTE post-spine surgery.
- Lumbar surgery and the use of elastic stockings were also associated with increased VTE risk.
- Further research and targeted preventative strategies are warranted for high-risk patient groups.
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